1,4-Cyclohexanedione, CAS 637-88-7, is an organic cyclic diketone used as a building block in chemical synthesis. Its six-membered carbon ring carries two ketone groups at the 1 and 4 positions, giving chemists two carbonyl sites for designing subsequent reactions. The molecular formula is C6H8O2, and its molar mass is 112.13 g/mol. For B2B purchasing, the key checks are identity, assay and impurity requirements, physical form, packaging, documentation, and whether the material suits the intended process.
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1,4-Cyclohexanedione is a six-carbon ring compound with ketone carbonyl groups on opposite sides of the ring. It is also described by its systematic structural name, cyclohexane-1,4-dione. The CAS number 637-88-7 helps distinguish it from other cyclohexanedione isomers and similarly named materials during sourcing and documentation checks.
Its two carbonyl groups make the compound useful as a synthetic starting material rather than simply a finished-use product. Depending on the reaction route, chemists may transform one or both carbonyl sites or use the ring as a framework for preparing more complex structures. Actual suitability depends on the target chemistry, reaction conditions, and the quality requirements of the downstream process.
The molecular formula is C6H8O2, with a molar mass of 112.13 g/mol. Commercial descriptions commonly identify 1,4-cyclohexanedione as a crystalline solid, often white to off-white in appearance. Appearance is a useful incoming inspection observation, but it cannot by itself establish chemical identity or purity.
Reported melting points are commonly in the range of 78–82 °C. A melting point result can help buyers compare a lot with its stated specification, but the observed value can depend on the method and sample condition. We recommend confirming the supplier’s test method and acceptance limits rather than treating a general reference range as a guaranteed product specification.
As a diketone, the material contains two reactive carbonyl functions. This structural feature is relevant when assessing its role in synthesis, but reaction performance cannot be inferred from structure alone. Buyers should evaluate it within the specific route, including solvent compatibility, reaction conditions, and the impurity profile that the process can tolerate.
For storage and handling, follow the supplier’s current safety data sheet and the procedures used at your facility. Keep the material in its specified packaging and protect it from conditions identified in the product documentation. Before scale-up, review the applicable hazard, personal protective equipment, and waste-handling requirements with your EHS team.
1,4-Cyclohexanedione is used as an intermediate or building block in organic synthesis and research-scale chemical development. Its ring structure and paired carbonyl groups can offer more than one point for chemical modification. This makes it relevant to projects where a substituted cyclic structure is needed as part of a larger molecule.
In pharmaceutical intermediate development, buyers may evaluate 1,4-cyclohexanedione as a starting material within a multi-step synthetic route. The material’s role and required quality are route-specific; the CAS number alone does not establish suitability for a regulated application. Development teams should define critical impurities, analytical methods, and documentation needs before moving from laboratory evaluation to larger procurement quantities.
Research laboratories and specialty chemical manufacturers may assess the compound for preparing derivatives or exploring reaction sequences. In these settings, a smaller evaluation quantity can help confirm solubility, reactivity, and process compatibility before a larger order is placed. Scale-up decisions should be based on the buyer’s own experimental results and process controls.
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Suppliers may offer the same CAS identity in different commercial specifications rather than as fundamentally different chemical types. Relevant differences can include assay target, impurity limits, packaging configuration, and the analytical documentation supplied with an order. Buyers should distinguish a stated grade or purity from a guaranteed attribute: the exact product specification must be confirmed for the requested lot.
For example, a buyer may request an assay target such as 98% minimum for quotation purposes, but this is an illustrative purchasing requirement, not a universal standard or a claim about every available lot. A higher assay target may not address every process concern if a particular impurity is critical. Where needed, specify both the assay method and individual impurity limits.
| Specification area | What to confirm |
|---|---|
| Product identity | Name, CAS 637-88-7, molecular formula, and any internal item code |
| Assay and impurities | Minimum assay, relevant impurity limits, and test methods |
| Physical properties | Appearance and, if required, a melting point acceptance range |
| Documentation | Available certificate of analysis, safety data sheet, and other order-specific documents |
| Commercial details | Quantity, packaging, shipment destination, lead-time estimate, and quotation validity |
Ask whether the certificate of analysis will be lot-specific and which test methods are used. If your process has a defined impurity profile or a downstream regulatory requirement, describe it during the quotation stage instead of relying on a general product description. Confirm packaging and shipping details against the product’s handling requirements and your receiving procedures.
Start with the function of the material in your route and identify which attributes can affect reaction performance or product quality. Set an assay target that is appropriate to your process, then decide whether particular impurities, moisture, or physical characteristics need explicit limits. If those limits are not yet established, consider evaluating a sample or initial lot under your own analytical and process controls.
Request written confirmation of the offered specification, available quantity, packaging, shipment terms, and estimated lead time. Confirm which documents can be provided for the specific order, and check that the product name and CAS number are consistent across the quotation, label, and batch documentation. Avoid assuming that a standard description automatically covers a custom impurity limit, special packaging, or a particular analytical method.
Price is only one part of a sourcing decision. Compare the offered quality, minimum order quantity, packaging suitability, delivery plan, and communication around specification questions. For production planning, consider whether the supplier can confirm availability and timing for the quantity and destination you need before you commit to a schedule.
At Maison Chemical, we support B2B inquiries for 1,4-Cyclohexanedione CAS 637-88-7 by discussing the buyer’s required specification, quantity, packaging, and destination. We can help clarify the product information and order documentation available for the requested supply. Availability, lead time, and commercial terms should be confirmed for each inquiry.
To help us respond efficiently, include your target assay, any critical impurity limits, required documents, order quantity, and delivery location. If the material is for a specific synthesis route, sharing non-confidential process requirements can also help frame the discussion. Our team can then advise on the next steps for quotation and technical review.
1,4-Cyclohexanedione CAS 637-88-7 is a cyclic diketone intermediate with formula C6H8O2 and a molar mass of 112.13 g/mol. Its two carbonyl groups make it a potential building block for organic synthesis, while its practical value depends on the chemistry and quality requirements of the intended application. Buyers should treat general property data as a starting point and confirm the actual lot specification, test methods, and documentation before ordering.
Your next step is to define the required assay and impurity limits, quantity, packaging, and delivery destination. Send those details to Maison Chemical to request current availability, order-specific documentation, and a quotation for your B2B requirement.
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